Advances in Understanding the Importance of Alpha-Linolenic Acid in our Diet
This article at a glance
- Results from a large prospective study in elderly people, the Cardiovascular Health Study, indicate that significant associations may exist between a higher dietary intake of alpha-linolenic acid (ALA) and a decreased risk of total and non-cardiovascular mortality. However, no relation between risk of mortality from various aspects of cardiovascular disease and ALA intake was found.
- In a pooled cohort study of eight prospective studies that covered >220,000 adults, no significant associations between ALA intake and risk of incident coronary heart disease were identified.
- In a controlled weight loss study of overweight adults, daily dietary supplementation with a high ALA dose may facilitate the selective lowering of a circulating marker of inflammation, YKL-40, not previously studied in relation to essential fatty acid intake.