Guest Articles and Invited Opinion

A Balanced Approach to Omega-3 Benefits

Bill Lands, Fellow, American Society for Nutrition, College Park, MD, USA Email: wemlands@att.net; Website: http://efaeducation.org/ Similarities and differences between the omega-3 (n-3) and omega-6 (n-6) essential nutrients have moved in and out of discussions over the past 50 years as the biomedical community explored their diverse actions in human health. Evidence-based misunderstandings and apparent contradictions easily occur whenever a portion of the whole is discussed without a broader context to keep a balanced perspective (e.g., 1). Current paradoxes about benefits and harm from n-3 and n-6 nutrients prompt me to…

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Should Infant Formula Provide Only DHA, or DHA along with Arachidonic Acid?

Berthold Koletzko1, Susan E. Carlson2, Johannes B. van Goudoever3 1Ludwig-Maximilians-University of Munich, Dr. von Hauner Children’s Hospital, Univ. of Munich Medical Center, München, Germany 2Univ. of Kansas Medical Center, Kansas City, KS, USA 3Depts. of Paediatrics, Emma Children’s Hospital, Academic Medical Center, and VU University Medical Center, Amsterdam, The Netherlands   Infancy and early childhood are characterized by very rapid growth and tissue differentiation, which induce extremely high nutrient needs per kg bodyweight, while body stores are still very limited and thus the infant cannot compensate well for unbalanced nutrient supplies…

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The 2013 Omega-3 Fatty Acid – Prostate Cancer Debacle

William S. Harris, PhD Senior Research Scientist, Health Diagnostic Laboratory, Inc. (Richmond, VA) Professor, Department of Internal Medicine, Sanford School of Medicine, University of South Dakota President, OmegaQuant Analytics, LLC (Sioux Falls, SD)   On July 11, 2013 a paper was published online by Brasky et al. in the J Natl Cancer Institute entitled, “Plasma Phospholipid Fatty Acids and Prostate Cancer Risk in the SELECT Trial.”(1) This paper was widely publicized across all media platforms, even finding its way onto the network evening news programs. What did the study actually…

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Omega-3 PUFAs: Who Could Have Predicted?

Guest Article Joyce A. Nettleton, D.Sc. Past Editor, PUFA Newsletter   How far omega-3 (n-3) PUFA research has come! The 1936 medical observations of Israel Rabinowitch describing the rarity of arteriosclerosis among the Inuit of the eastern Canadian Arctic and similarly among the northwest Greenlanders led to the report of high levels of long-chain omega-3 PUFAs (n-3 LC-PUFAs) in Inuit plasma lipids by Bang and Dyerberg. Finally, Dyerberg and colleagues suggested that high levels of n-3 LC-PUFAs were linked to the prevention of thrombosis and CVD. The involvement of these…

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Clinical Studies on the Effect of Omega-3 Fatty Acids on Cardiovascular Outcomes

Invited Opinion Aldo Bernasconi, Ph.D. Director of Information and Research Global Organization for EPA and DHA Omega-3s   There is a long history of clinical research showing that long-chain omega-3 fatty acids – the kind of fatty acids found at relatively high levels in fish oils – have a cardio-protective effect. This research includes several large randomized control trials (RCTs). These trials, in which participants are randomly selected to receive either a treatment or a placebo, have long been considered to be the gold standard for clinical research. One surprising…

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Nutrition, Omega-3 Fatty Acids and Depression

By Marlene P. Freeman, M.D., Associate Professor of Psychiatry, Harvard Medical School, Boston, Mass. The effects of nutrition and dietary composition have been studied in the area of mental health.  Epidemiological studies have focused either on cross-sectional analyses or longitudinal analysis on intake of particular nutrients or patterns of intake. Treatment studies have used dietary supplementation for psychiatric disorders, particularly major depressive disorder (MDD). Depression and anxiety disorders are more prevalent in women than men.1 MDD consists of episodes that are of at least two weeks’ duration and is characterized…

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ISSFAL 2012

The 10th Congress of the International Society for the Study of Fatty Acids and Lipids (ISSFAL) convened May 26-30, in Vancouver, Canada, overlooking the North Shore Mountains, Coal Harbor and Stanley Park. Three days packed with meetings, breakfast workshops, plenary and poster sessions, exhibits and a gala dinner brought together scientists and others from 33 countries. All share an interest in current research on the biochemistry, health effects and genomics of fatty acids and lipids. The conference program and abstracts can be downloaded here. Selected highlights from the meeting include:…

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