Clinical Conditions

Dietary Long-Chain Omega-3s Linked to Lower Risk of Colorectal Polyps in Women

[frame src=”/wp-content/uploads/images/PUFA4.12_Photo12.1.png” alt=”” width=”216″ height=”262″ align=”right”]The most effective preventive strategy for colorectal cancer, which is the third most common cancer in the U.S., is the detection of its earliest abnormalities, polyps in the colon or rectum. These precancerous lesions are detected by colonoscopy, a visual inspection of the colon. The doctor will remove any abnormal polyps during the procedure. Because colorectal cancer usually does not reveal itself until the condition is advanced, looking for its earliest warning signs offers the greatest protection. A recent study reported a 77% lower risk…

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Muscle Strength: Build it Better with Fish Oil and Strength Training

[frame src=”/wp-content/uploads/images/FOL4.12_Photo10.png” width=”261″ height=”221″ align=”left”]With aging and reduced physical activity, skeletal muscles lose some of their strength, functional capacity and mass. With greater muscle weakness, an individual may be less able to get around and care for him/herself and usually face a greater risk of bone fracture and mortality. Many of these changes can be substantially slowed and muscle performance improved with appropriate physical activity and exercise, strength training and healthy nutrition. There are now many studies in older adults showing the health benefits of physical activities from alpine skiing…

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Higher Long-Chain Omega-3s Linked to Lower Risk of Colorectal Polyps in Women

[frame src=”/wp-content/uploads/images/FOL4.12_Photo12.1.png” alt=”” width=”216″ height=”262″ align=”left”]The most effective preventive strategy for colorectal cancer, which is the third most common cancer in the U.S., is finding and removing its earliest abnormalities. These appear as polyps or small sacs in the colon or rectum (Illustration) and are detected during a colonoscopy exam. They are considered precancerous. Because colorectal cancer usually does not reveal itself until the disease is advanced, looking for its earliest warning signs offers the greatest protection. A recent study reported that adults 50 years of age or older who…

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Preterm Infants Given Fish Oil Emulsions May Have Less Retinopathy of Prematurity

Preterm infants born before 36 weeks’ gestation or those born weighing less than 1,250 grams are at high risk of mortality and morbidity, with risk increasing as gestational age decreases. Recently published findings from the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network on the mortality and morbidity of nearly 10,000 infants of extremely low gestational age and birthweight describe the high rates of illness among the survivors. Early nutritional support reduces the severity of illness in these infants, though attention to LC-PUFAs has…

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Positive Effects of DHA in Experimental Traumatic Brain Injury

Traumatic brain injury results in 53,000 deaths in the U.S. every year (Figure), with nearly twice that number suffering permanent disability, including diminished cognitive ability. Treatments with long-term benefits are few and of limited effectiveness.  Progesterone may have neurological benefits and is in a Phase III clinical trial for patients with moderate-to-severe traumatic brain injury. Attention has also turned to the potential effects of DHA in preventing and ameliorating traumatic brain and spinal cord injury. DHA involvement in neuronal membrane structure and function, learning and memory, as well as neuroplasticity…

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Eicosapentaenoic Acid and Docosahexaenoic Acid: Are They Different?

Trevor A Mori, Ph.D., Professor, School of Medicine and Pharmacology, Royal Perth Hospital Unit, University of Western Australia, Perth, Australia. Many of the cardiovascular benefits ascribed to omega-3 (n-3) fatty acids were initially attributed to eicosapentaenoic acid (EPA) rather than docosahexaenoic acid (DHA). It was suggested that some of the effects of EPA were due to its being a competitive inhibitor of arachidonic acid for the cyclooxygenase and lipoxygenase enzymes, leading to prostaglandins and leukotrienes with attenuated bioactivity compared with the respective arachidonic acid analogues. However, we now know that…

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