EPA for Retinal Neuron DHA Synthesis

This article at a glance Photoreceptor cells contain high levels of DHA in their outer light-sensitive segment. Past research had shown that the DHA in photoreceptors was obtained from hepatic synthesis transported via the circulation, as well as from local synthesis in the retinal pigment epithelial cells that support photoreceptor function. New research indicates that

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Addressing the Potential of an Adjunct Therapeutic Role for Supplemental EPA/DHA in VEGF-A-Mediated Wet Age-Related Macular Degeneration

This article at a glance VEGF inhibitors have significantly improved the treatment of neovascular age-related macular degeneration (wet AMD). In a pilot study, the possible adjunct therapeutic potential for omega-3 LCPUFA supplementation to lower the intravitreal levels of VEGF, as a central mediator for neovascularization, has been addressed in wet AMD patients treated with anti-VEGF

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Long-Chain Omega-3s and High-Dose Vitamin A Slow Visual Loss in Retinitis Pigmentosa

[frame src=”/wp-content/uploads/images/PUFA4.12_Photo4.1.png” alt=”” width=”238″ height=”264″ align=”right” ]Retinitis pigmentosa is an eye disease of genetic origin that slowly damages the retina and impairs vision. It is usually first noticed by poor night vision, which progresses gradually to impaired peripheral vision (tunnel vision), then loss of central vision. The hallmark of the condition is black spicule-shaped deposits

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DHA Restriction Leads to Distortions in Visual Pathways in Early Development

[frame src=”/wp-content/uploads/images/PUFA4.12_Callout15.png” alt=”” width=”190″ height=”178″ align=”left”]The development of visual pathways from the retina to the visual cortex in the brain involves the proper arrangement of retinal neuronal axons within two brain structures along the route. These structures, the superior colliculus and the lateral geniculate nucleus, require precise alignment (topography) of the neural connections from the

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Increased Corneal Nerve Regeneration and Function with DHA Plus PEDF After Injury

[frame src=”/wp-content/uploads/images/PUFA4.12_Callout17.png” alt=”” width=”190″ height=”192″ align=”left” ]This issue of the PUFA Newsletter reports research demonstrating that injured peripheral neurons are more resistant to damage from injury and recover more quickly and extensively when cellular concentrations of DHA and docosapentaenoic acid (DPA n-3) are elevated. In this article, Haydee Bazan and colleagues at Louisiana State University

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