New Insight into the Retinopathy of Prematurity

This article at a glance A recent intervention study that evaluated the usefulness of supplementing the parenteral feed of premature babies with long-chain omega-3 fatty acids to alleviate the retinopathy frequently associated with premature birth was unsuccesful. An assessment of the fatty acid levels in the prematurely-born babies now indicates that low levels of arachidonic

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EPA for Retinal Neuron DHA Synthesis

This article at a glance Photoreceptor cells contain high levels of DHA in their outer light-sensitive segment. Past research had shown that the DHA in photoreceptors was obtained from hepatic synthesis transported via the circulation, as well as from local synthesis in the retinal pigment epithelial cells that support photoreceptor function. New research indicates that

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Addressing the Potential of an Adjunct Therapeutic Role for Supplemental EPA/DHA in VEGF-A-Mediated Wet Age-Related Macular Degeneration

This article at a glance VEGF inhibitors have significantly improved the treatment of neovascular age-related macular degeneration (wet AMD). In a pilot study, the possible adjunct therapeutic potential for omega-3 LCPUFA supplementation to lower the intravitreal levels of VEGF, as a central mediator for neovascularization, has been addressed in wet AMD patients treated with anti-VEGF

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DHA Restriction Leads to Distortions in Visual Pathways in Early Development

[frame src=”/wp-content/uploads/images/PUFA4.12_Callout15.png” alt=”” width=”190″ height=”178″ align=”left”]The development of visual pathways from the retina to the visual cortex in the brain involves the proper arrangement of retinal neuronal axons within two brain structures along the route. These structures, the superior colliculus and the lateral geniculate nucleus, require precise alignment (topography) of the neural connections from the

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