Gaining Control over Physical Aggression

This article at a glance A recent, carefully controlled study, has investigated whether daily supplementation with EPA/DHA could attenuate physical aggresion. The study reports an important reduction in the level of self-reported physical aggression. The World Health Organization defines intentional injuries as largely preventable events resulting from aggression and violence. Interpersonal violence-related mortality includes deaths

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Omega-3 LCPUFA Chemical Oxidation Pathways Associated with Cognitive Disorders

This article at a glance Neuroprostanes are oxidation products of DHA that are produced endogenously via non-enzymatic pathways. The chemical structure and biological activity has only been characterized for some of the neuroprostanes. This study reports that two neuroprostanes, 4-F4t-NeuroP and 10-F4t-NeuroP, are found at elevated levels in patients with multiple scleroris, Down syndrome, Rett

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Failure to Replicate Findings on Omega-3 LCPUFA Supplementation on the Transition to Psychotic Disorder in Individuals at Ultra-High Risk

This article at a glance Psychotic disorders encompass serious psychiatric disorders, manifesting themselves in the altered perception of reality, such as delusions or hallucinations, disorganized or bizarre behaviors and “negative” symptoms, which include flatness of emotion and interpersonal relations and amotivation. Psychotic disorders, when chronic, are characterized by low functioning and a poor prognosis. A

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Identifying People with Depressive Symptoms that May Benefit Most from Omega-3 Fatty Acid Consumption

This article at a glance In an observational study of a cohort of Puerto Ricans, only those individuals with the highest level of urinary 8-hydroxy-2´-deoxyguanosine (8-OHdG), a marker of oxidative stress, showed an inverse relationship between the omega-3 index (combined EPA and DHA as percentage of red blood cell fatty acids) and depressive symptoms. The

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EPA/DHA – Perspectives for Neuropsychological Improvement in Malnourished Pre-adolescent Children

Malnutrition, defined by insufficient energy and protein intake, seriously affects cognitive functions. Nutritional deficiencies early in a child’s development have marked consequences for cognitive development and overall growth at later ages of development. Malnutrition is a preventable malady but is tightly linked to low socio-economic status, hampering implementation of corrective strategies. Along with insufficient energy

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Addressing Depression in Maintenance Hemodialysis Patients

In end-stage renal disease, over 90% of kidney function has been lost. Hemodialysis has long been a solution to prolong the life of end-stage renal disease patients. Depressive symptoms and distress are very common in chronic hemodialysis patients with end-stage renal disease, with an estimated prevalence rate of 20 to 70%. Longitudinal studies have shown

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Omega-3 PUFAs: Who Could Have Predicted?

Guest Article Joyce A. Nettleton, D.Sc. Past Editor, PUFA Newsletter   How far omega-3 (n-3) PUFA research has come! The 1936 medical observations of Israel Rabinowitch describing the rarity of arteriosclerosis among the Inuit of the eastern Canadian Arctic and similarly among the northwest Greenlanders led to the report of high levels of long-chain omega-3

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EPA Significantly Reduces Depressive Episodes in Interferon-Alpha-Treated Hepatitis C Patients

Interferons are a class of cytokines with important immunoregulatory properties, including antiviral and anticarcinogenic effects. They are especially important in the body’s innate immune response to viral infections and are widely used in the primary and adjunct treatment of hepatitis B and C viruses, cancer, such as malignant melanoma and certain leukemias, and in multiple

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