Maternal Plasma Docosahexaenoic Acid (DHA) Concentrations Increase at the Critical Time of Neural Tube Closure

  Barbara J Meyer (University of Wollongong, Australia) Dilys J Freeman (University of Glasgow, UK)   Docosahexaenoic acid (DHA) and polyunsaturated fatty acid (PUFA) metabolism DHA is an omega-3 long chain polyunsaturated fatty acid (n-3 LCPUFA) containing 22 carbons and 6 carbon to carbon double bonds denoted as 22:6n-3. It is an n-3 fatty acid

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Bronchopulmonary Dysplasia in Preterm Infants – Understanding the Physiological Changes in AA and DHA during Gestation

This article at a glance Bronchopulmonary dysplasia is a form of lung injury caused by assisted ventilation and oxygen support compounding an incomplete development of lung tissue observed in very early and low birth weight preterm infants. In a study of fetal fatty acid (LCPUFA) accretion during the third trimester of pregnancy, the level of

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Is Arachidonic Acid Required to Balance Docosahexaenoic Acid in Infant Feeding for Proper Development?

Thomas Brenna Division of Nutritional Sciences Cornell University Ithaca, NY 14853 USA jtb4@cornell.edu / 607-255-9182   The long chain polyunsaturated fatty acids (LC-PUFA) docosahexaenoic acid (DHA) and arachidonic acid (AA, or ARA) are conserved components of the breast milks of all well-nourished mothers worldwide. Since at least the mid-1990s, they have been permitted as components of

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Understanding Defects in Fatty Acid Mobilization to Safeguard Fetal DHA Accretion in Gestational Diabetes

This article at a glance This study documented the changes in circulating levels of various fatty acids during the third trimester of pregnancy complicated by gestational diabetes. In gestational diabetes, defects in the mobilization of several fatty acids were identified, including the DHA necessary for accretion by the fetus. In a separate controlled intervention study,

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Enhanced Production of Breast Milk DHA during Chia Oil Intake

This article at a glance A randomized controlled intervention trial has addressed the effect of chia oil intake during pregnancy and nursing on breast milk fatty acid composition in healthy women. In addition to increased levels of alpha-linolenic acid, a marked elevation in docosahexaenoic acid (DHA) in breast milk is observed during the first three

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Advances in Understanding the Relationship between Child Problem Behavior and Maternal Long-Chain PUFA Intake

This article at a glance An important area in omega-3 research addresses the possibility to prevent or alleviate ADHD in childhood by omega-3 supplementaton with omega-3 LCPUFA of mothers during pregnancy or the children with ADHD themselves. A higher n-3:n-6 ratio during mid-pregnancy was found to be associated with fewer emotional, but not behavioral, problems

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Assessing the Effectiveness of Omega-3 Long-Chain Polyunsaturated Fatty Acids in Environmental Enteropathy in Children

This article at a glance Environmental enteropathy is increasingly being recognized to contribute to nutrient malabsorption and augmented catabolism in young children living in conditions where fecal to oral contamination occurs constantly. Besides improving sanitary conditions, no effective medical interventions have been clearly identified to improve environmental enteropathy. In this study the effectiveness in environmental enteropathy of

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Increased Length of Gestation Linked with Self-reported Omega-3 Use during Pregnancy in Women at High Risk due to Psychiatric and Psychotropic Use

This article at a glance In this report the authors demonstrate that omega-3 fatty acids should be researched further as a variable to decrease obstetrical risk in women with psychiatric disorders Further research is needed as the data is consistent with the existing literature that omega-3 fatty acids can lengthen gestation. It is not yet

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Should Infant Formula Provide Only DHA, or DHA along with Arachidonic Acid?

Berthold Koletzko1, Susan E. Carlson2, Johannes B. van Goudoever3 1Ludwig-Maximilians-University of Munich, Dr. von Hauner Children’s Hospital, Univ. of Munich Medical Center, München, Germany 2Univ. of Kansas Medical Center, Kansas City, KS, USA 3Depts. of Paediatrics, Emma Children’s Hospital, Academic Medical Center, and VU University Medical Center, Amsterdam, The Netherlands   Infancy and early childhood are

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