Guidelines and EPA+DHA: Irreconcilable?

  Prof. Dr. C. von Schacky, Preventive Cardiology, Med Clinic I, University of Munich, and Omegametrix, Martinsried, both Germany. Email: Clemens.vonSchacky@med.uni-muenchen.de   Cardiac societies, like the American Heart Association (AHA) or the European Society of Cardiology (ESC), periodically publish guidelines, among them on primary or secondary prevention of cardiovascular disease (AHA) or cardiovascular prevention (ESC)

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Maternal Plasma Docosahexaenoic Acid (DHA) Concentrations Increase at the Critical Time of Neural Tube Closure

  Barbara J Meyer (University of Wollongong, Australia) Dilys J Freeman (University of Glasgow, UK)   Docosahexaenoic acid (DHA) and polyunsaturated fatty acid (PUFA) metabolism DHA is an omega-3 long chain polyunsaturated fatty acid (n-3 LCPUFA) containing 22 carbons and 6 carbon to carbon double bonds denoted as 22:6n-3. It is an n-3 fatty acid

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Enhancing Breast Cancer Treatment with Omega-3 Fatty Acids

Miranda Brun, PhD and Catherine J. Field, PhD RD Department of Agricultural, Food and Nutritional Science University of Alberta, Edmonton, Alberta, Canada   In North America and Europe, breast cancer accounts for over 25% of all new cancer diagnoses in women, and approximately 1 in 8 women will be diagnosed with breast cancer in their

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F3-Isoprostanes and F4-Neuroprostanes: Non-enzymatic Cyclic Oxygenated Metabolites of Omega-3 Polyunsaturated Fatty Acids: Biomarkers and Bioactive Lipids

Jean-Marie Galano, Camille Oger, Valérie Bultel-Poncé, Guillaume Reversat, Alexandre Guy, Joseph Vercauteren, Claire Vigor, Thierry Durand. Institut des Biomolécules Max Mousseron (IBMM), UMR 5247, CNRS, Université de Montpellier, ENSCM, Montpellier, France.   Thierry Durand Institut des Biomolécules Max Mousseron (IBMM), UMR 5247, CNRS, Université de Montpellier, ENSCM, Montpellier (France). Phone: +33 4 11 75 95

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Is Arachidonic Acid Required to Balance Docosahexaenoic Acid in Infant Feeding for Proper Development?

Thomas Brenna Division of Nutritional Sciences Cornell University Ithaca, NY 14853 USA jtb4@cornell.edu / 607-255-9182   The long chain polyunsaturated fatty acids (LC-PUFA) docosahexaenoic acid (DHA) and arachidonic acid (AA, or ARA) are conserved components of the breast milks of all well-nourished mothers worldwide. Since at least the mid-1990s, they have been permitted as components of

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On the Contribution of Plasma Lysophospholipid and Non-Esterified Docosahexaenoic Acid to the Brain

Richard P. Bazinet Associate Professor, Canada Research Chair in Brain Lipid Metabolism Department of Nutritional Sciences, Faculty of Medicine, University of Toronto FitzGerald Building, 150 College Street, Room 306 Toronto, ON, Canada M5S 3E2 Email – richard.bazinet@utoronto.ca   The brain has a lot of docosahexaenoic acid The brain is particularly enriched with the polyunsaturated fatty

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The Impact of Common Gene Variants on EPA and DHA Status and Responsiveness to Increased Intakes

Professor Anne Marie Minihane Department of Nutrition and Preventive Medicine, Norwich Medical School, University of East Anglia (UEA), Norwich, UK Website: https://www.uea.ac.uk/medicine/people/profile/a-minihane   Setting the Scene A large body of human prospective epidemiology, as well as rodent feeding studies, have demonstrated the beneficial impact of the “marine” long chain n-3 PUFA (LC n-3 PUFA), EPA

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Metabolic Effects of Long Chain n-3 Fatty Acids: Implications for Prevention of Diabetes

Professor Jacques Delarue, MD, PhD Department of Nutritional Sciences & Laboratory of Human Nutrition University Hospital/Faculty of Medicine/University of Brest, France jacques.delarue@univ-brest.fr   Type 2 diabetes (T2D) is a worldwide increasing non-communicable disease characterized by the association with insulin-resistance and defects in insulin secretion. The main factors explaining this increasing prevalence beyond polygenic predisposition are

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The 2013 Omega-3 Fatty Acid – Prostate Cancer Debacle

William S. Harris, PhD Senior Research Scientist, Health Diagnostic Laboratory, Inc. (Richmond, VA) Professor, Department of Internal Medicine, Sanford School of Medicine, University of South Dakota President, OmegaQuant Analytics, LLC (Sioux Falls, SD)   On July 11, 2013 a paper was published online by Brasky et al. in the J Natl Cancer Institute entitled, “Plasma

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Omega-3 PUFAs: Who Could Have Predicted?

Guest Article Joyce A. Nettleton, D.Sc. Past Editor, PUFA Newsletter   How far omega-3 (n-3) PUFA research has come! The 1936 medical observations of Israel Rabinowitch describing the rarity of arteriosclerosis among the Inuit of the eastern Canadian Arctic and similarly among the northwest Greenlanders led to the report of high levels of long-chain omega-3

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