The Effect of Macronutrient Composition on Endogenous Long-Chain Polyunsaturated Fatty Acid Status during Weight Loss

This article at a glance The influence on tissue fatty acid composition of three different isocaloric diets  containing carbohydrates with a low glycemic index, carbohydrates with a high glycemic index, or a reduced fat content, respectively, was assessed in overweight-obese adults on a 500 kcal/d-energy restriction in a randomized controlled intervention trial. The study had

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Omega-3 LCPUFA Intake-Induced Molecular Changes in Type 2 Diabetes

This article at a glance The effects of omega-3 long-chain polyunsaturated fatty acids (LCPUFA) on deranged glucose homeostasis in type 2 diabetics are incompletely understood. Metabolomic analyses of blood samples from two recent randomized controlled clinical trials in American and Chinese adults with type 2 diabetes link omega-3 LCPUFA supplementation to changes in branched-chain amino

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Indications for an Association between Higher PUFA Intake with Improved Lean Mass and Reduced Adiposity in Children

This article at a glance This study addressed if any associations exist between self-reported dietary intake of polyunsaturated fatty acids and obesity in 7-12 year old US American children from a racially diverse background. Associations were identified between higher total PUFA intake and lower body fat and intra-abdominal adipose tissue. Total dietary PUFA intake, as

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No Change in Upper Gastrointestinal Complications from Low-Dose Aspirin with Concurrent Prescription Omega-3 Fatty Acid Intake

This article at a glance This study assessed if in a large group of patients taking low-dose aspirin for thromboprophylactic purposes during their otherwise daily life, the concurrent use of prescription omega-3 fatty acids would affect the incidence of upper-gastrointestinal complications. Drawing from a large patient register, the authors determined that concurrent use of low-dose

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Sustaining DHA Accretion during Recovery from Acute Malnutrition with Improvements in Ready-to-Use-Therapeutic Foods

This article at a glance Two recent studes have explored the possibility of adjusting the fatty acid composition of Ready-to-Use Therapeutic Foods (RUTF) that are used to rehabilitate malnourished children, with the aim of better supporting omega-3 LCPUFA status. DHA levels drop during the recovery of malnourished children treated with a standard RUTF – this

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Omega-3 LCPUFA Supplementation; Activating a Protective Cardiovascular Response in Patients with Advanced Chronic Kidney Disease

This article at a glance In this report the authors present the changes in plasma levels of EPA- and DHA-derived lipid mediators in response to an eight-week supplementation with omega-3 LCPUFA in patients with advanced chronic kidney disease. Importantly the study shows that even in an advanced disease state the body remains capable of mounting

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Omega-3s for Male Fertility

This article at a glance Two recent studies have addressed the role of omega-3 LCPUFA in varicocele and asthenozoospermia, two relatively common disorders of male fertility. Higher dietary intake of EPA, DHA and total omega-3 LCPUFA was found to be associated with a reduced probability to suffer asthenozoospermia. In infertile men with varicocele, the levels

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Successful Treatment of Common Acne with 3 Months EPA/DHA

This article at a glance This is the first controlled study to address the potential effectiveness of daily EPA/DHA for common acne in young adults. The study reports — through both objective scores, and subjective assessment — decreased acne severity in young adults. The results are supported by histological analyses that signal a reduction in

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